Academic Resume
Education
1999.10 - 2002.5 Post-doctor, Cancer Center, Sun Yat-sen University Major: Clinical Oncology
1992.9 - 1998.7 M.D., Ph.D., Academy of Chinese Medical Sciences, Peking Union Medical College Major:Epidemiology
1987.9 - 1992.7 Bachelor of Medicine (Preventive Medicine), School of Public Health, Shanxi Medical College
Position and Employment
2006.12 - present Professor, Cancer Center, Sun Yat-sen University
2002.05 - 2006.12 Associate Professor, Cancer Center, Sun Yat-sen University
Professional Affiliations
Vice-chairman, Branch for Tissue Bio-Bank, China Medicinal Biotech Association
Member of China Anti-Cancer Association Committee, Branch for Cancer Epidemiology
Member of China Anti-Cancer Association Committee, Branch for Cancer Etiologyy
Member of Guangdong Medical Association Committee, Branch for Medical Genetics
Editor in charge, Chinese Journal Cancer
Teaching and Scientific Research
Grants
1．PI: The National Natural Science Fund for Distinguished Young Scholars（No. 81325018）, Epidemiology(2014-2017), RMB 3,200,000
2．PI: The key project for International Cooperation and Exchange of the National Natural Science Foundation of China (Grant No. 81220108022), Identifying causal variations for nasopharyngeal carcinoma by family-based whole-genome sequencing technology and functional study.(2013-2017), RMB 2,800,000
3．M-PI: National Key Scientific and Technological Project (2011ZX09307-001-04), Facility of Clinical tumor resource (2011-2013) RMB 1,600,000
4．Principal participant, China, The Ministry of Science and Technology Award of China (2011CB504303) ,973 project: Basic Research of Virus Carcinogenesis and Intervene, 2011-2015, RMB 700, 000.
5．Principal participant, China, The Ministry of Science and Technology Award of China (2012AA02A501) ,863 project: Nasopharyngeal Carcinoma molecular staging and individual diagnosis and treatment, 2012-2015, RMB 500, 000.
6．Co-PI of China: National Cancer Institute, National Institutes of Health(No.#R01CA115873-01), Gene-Environment-EBV Interaction in the Etiology of Nasopharyngeal Carcinoma (2010-2014)，RMB 1,000,000
Selected Publication
1. Tan DE, Foo JN, Bei JX, Chang J, Peng R, Zheng X, Wei L, Huang Y, Lim WY, Li J, Cui Q, Chew SH, Ebstein RP, Kuperan P, Lim ST, Tao M, Tan SH, Wong A, Wong GC, Tan SY, Ng SB, Zeng YX, Khor CC, Lin D*, Seow AL*, Jia WH*, Liu J*. Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population. Nat Genet. 2013 Jun 9;45(7):804-7. (IF=29.352)
2. Jia WH*, Zhang B, Matsuo K, Shin A, Xiang YB, Jee SH, Kim DH, Ren Z, Cai Q, Long J, Shi J, Wen W, Yang G, Delahanty RJ; Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO); Colon Cancer Family Registry (CCFR), Ji BT, Pan ZZ, Matsuda F, Gao YT, Oh JH, Ahn YO, Park EJ, Li HL, Park JW, Jo J, Jeong JY, Hosono S, Casey G, Peters U, Shu XO, Zeng YX, Zheng W. Genome-wide association analyses in east Asians identify new susceptibility loci for colorectal cancer. Nat Genet. 2013, 45(2):191-6. (IF=29.352)
3. Chen K* , Ma H , Li L , Zang R , Wang C , Song F , Shi T , Yu D, Yang M, Xue W, Dai J, Li S, Zheng H, Wu C, Zhang Y, Wu X, Li D, Xue F,Li H, Jiang Z, Liu J, Liu Y, Li P, Tan W, Han J, Jie J, Hao Q, Hu Z, Lin D, Ma D*, Jia WH*, Shen H*, Wei Q*. Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women. Nat Commun 2014, 5: 4682. (IF=11.47)
4. Xu FH, Xiong D，Xu YF, Cao SM, Xue WQ, Qin HD, Liu WS, Cao JY, Zhang Y, Feng QS, Chen LZ, Li MZ, Liu ZW, Liu Q, Hong MH, Shugart YY, Zeng YX , Zeng MS*, Jia WH*. An epidemiological and molecular study of the relationship between smoking, risk of nasopharyngeal carcinoma, and epstein-barr virus activation. J Natl Cancer Inst. 2012 Sep 19;104(18):1396-410. (IF=12.583)
5. Jia WH*, Qin HD. Non-viral environmental risk factors for nasopharyngeal carcinoma: A systematic review. Semin Cancer Biol. 2012 Apr;22(2):117-26. (IF=9.33)
6. Qin HD, Shugart YY, Bei JX, Pan QH, Chen L, Feng QS, Chen LZ, Huang W, Liu JJ, Jorgensen TJ, Zeng YX, Jia WH*. Comprehensive pathway-based association study of DNA repair gene variants and the risk of nasopharyngeal carcinoma. Cancer Res. 2011, 71(8):3000-8. (IF=9.329)
7. He J, Liao XY, Zhu JH, Xue WQ, Shen GP, Huang SY, Chen W, Jia WH*. Association of MTHFR C677T and A1298C polymorphisms with non-Hodgkin lymphoma susceptibility: evidence from a meta-analysis. Sci Rep 2014;4: 6159. (IF=5.578)
8. Xue WQ, He YQ, Zhu JH, Ma JQ, He J, Jia WH*. Association of BRCA2 N372H polymorphism with cancer susceptibility: a comprehensive review and meta-analysis. Sci Rep 2014;4: 6791. (IF=5.578)
9. Xue WQ, Qin HD, Ruan HL, Shugart YY, Jia WH*.Quantitative association of tobacco smoking with the risk of nasopharyngeal carcinoma: A comprehensive meta-analysis of studies conducted between 1979-2011. Am J Epidemiol 2013 Aug 1;178(3):325-38. (IF=5.23)
10. Shen GP, Pan QH, Hong MH, Qin HD, Xu YF, Chen LZ, Feng QS, Jorgensen TJ, Shugart YY, Zeng YX, Jia WH*. Human genetic variants of homologous recombination repair genes first found to be associated with Epstein-Barr virus antibody titers in healthy Cantonese. Int J Cancer. 2011 Sep 15;129(6):1459-66. (IF=5.085)
11. Ruan HL, Qin HD, Shugart YY, Bei JX, Luo FT, Zeng YX*, Jia WH*. Developing genetic epidemiological models to predict risk for nasopharyngeal carcinoma in high-risk population of China. PLoS One. 2013; 8(2): e56128. doi: 10.1371/ journal.pone. 0056128. (IF=3.234)
12. Ge XS, Ma HJ, Zheng XH, Ruan HL, Liao XY, Xue WQ, Chen YB, Zhang Y, Jia WH*. HOTAIR, a prognostic factor in esophageal squamous cell carcinoma, inhibits WIF-1 expression and activates Wnt pathway. Cancer Sci. 2013 Dec;104(12):1675-82. (IF=3.523)
13. Shen GP, Xu FH, He F, Ruan HL, Cui C, Chen LZ, Zeng YX, Jia WH*. Pretreatment lifestyle behaviors as survival predictors for patients with nasopharyngeal carcinoma. PLoS One. 2012;7(5):e36515. (IF=3.234)
14. He YQ, Zhu JH, Huang SY, Cui Z, He J, Jia WH*. The association between the polymorphisms of TNF-alpha and non-Hodgkin lymphoma: a meta-analysis. Tumour Biol 2014;35: 12509-17. (IF=3.611)
15. Li Y, Wen ZS, Yang HX, Luo RZ, Zhang Y, Zhang MF, Wang X*, Jia WH*. High expression of Y-Box-Binding protein-1 is associated with poor survival in resectable esophageal squamous Cell carcinoma. Ann Surg Oncol. 2011 Nov;18(12):3370-6. (IF=3.93)
16. Li Y, Yang HX, Luo RZ, Zhang Y, Li M, Wang X*, Jia WH*. High expression of p300 has an unfavorable impact on survival in resectable esophageal squamous cell carcinoma. Ann Thorac Surg. 2011, 91(5):1531-8. (IF=3.849)
17. He J, Wang F, Zhu JH, Chen W, Cui Z, Jia WH*. No association between MTR rs1805087 A > G polymorphism and non-Hodgkin lymphoma susceptibility: evidence from 11 486 subjects. Leuk Lymphoma 2014: 1-5. (IF=2.891)
18. Li CF, Luo FT, Zeng YX, Jia WH*. Weighted risk score-based multifactor dimensionality reduction to detect gene-gene interactions in nasopharyngeal carcinoma. Int J Mol Sci 2014;15: 10724-37. (IF=2.862)
19. Zheng XH, Cui C, Ruan HL, Xue WQ, Zhang SD, Hu YZ, Zhou XX, Jia WH*. Plasma microRNA profiling in nasopharyngeal carcinoma patients reveals miR-548q and miR-483-5p as potential biomarkers. Chin J Cancer 2014;33: 330-8. (IF=2.155)
20. He F, Zou JT, Zhou QF, Niu DL, Jia WH*. Glatiramer acetate reverses cognitive deficits from cranial-irradiated rat by inducing hippocampal neurogenesis. J Neuroimmunol 2014;271: 1-7.(IF=2.467)
21. Jia WH*, Luo XY, Feng BJ, Ruan HL, Bei JX, Liu WS, Qin HD, Feng QS, Chen LZ, Yao SY, Zeng YX. Traditional Cantonese diet and nasopharyngeal carcinoma risk: a large-scale case-control study in Guangdong, China. BMC Cancer. 2010 Aug 20;10:446. (IF=3.362)
22. He JR, Qin H, Ren ZF*, Cui C, Zhang Y, Ranatunga D, Zeng YX, Jia WH*. MMP-9 expression in peripheral blood mononuclear cells and the association with clinicopathological features and prognosis of nasopharyngeal carcinoma. Clin Chem Lab Med. 2011, 49(4):705-10. (IF=2.707)
23. He JR, Shen GP, Ren ZF*, Qin H, Cui C, Zhang Y, Zeng YX, Jia WH*. Pretreatment levels of peripheral neutrophils and lymphocytes as independent prognostic factors in patients with nasopharyngeal carcinoma. Head Neck. 2012 Feb 9. 2012 Dec;34(12):1769-76. (IF=2.641)
24. Fan Q, He JF, Wang QR, Cai HB, Sun XG, Zhou XX, Qin HD, Shugart YY, Jia WH*. Functional polymorphism in the 5'-UTR of CR2 is associated with susceptibility to nasopharyngeal carcinoma. Oncol Rep .2013; 30 (1):11-6. (IF=2.301)
25. Ge X, Chen Y, Liao X, Liu D, Li F, Ruan H, Jia WH*. Overexpression of long noncoding RNA PCAT-1 is a novel biomarker of poor prognosis inpatients with colorectal cancer. Med Oncol. 2013 Jun;30(2):588. doi: 10.1007/s12032-013-0588-6. (IF=2.058)
26. Li Y, Yu H, Luo RZ, Zhang Y, Zhang MF, Wang X*, Jia WH*. Elevated expression of Rad51 is correlated with decreased survival in resectable esophageal squamous cell carcinoma. J Surg Oncol. 2011 Nov 1;104(6):617-22. (IF=2.843)
27. Qin HD, Jia WH*, Zhang LL, Liu N, Zhou XX, Wang MH, Feng QS, Chen LZ, Zhang Y, Jorgensen TJ, Zeng YX, Shugart YY*. Elevated Epstein-Barr virus seroreactivity among unaffected members of families with nasopharyngeal carcinoma. J Med Virol. 2011 Oct;83(10):1792-8. (IF=2.217)
28. Xu YF, Liu WL, Dong JQ, Liu WS, Feng QS, Chen LZ, Zeng YX, Zeng MS, Jia WH*. Sequencing of DC-SIGN promoter indicates an association between promoter variation and risk of nasopharyngeal carcinoma in cantonese. BMC Med Genet. 2010 Nov 11;11:161. (IF=2.45)
29. Ren ZF, Liu WS, Qin HD, Xu YF, Yu DD, Feng QS, Chen LZ, Shu XO, Zeng YX, Jia WH*. Effect of family history of cancers and environmental factors on risk of nasopharyngeal carcinoma in Guangdong, China. Cancer Epidemiol. 2010 Aug;34(4):419-24. (IF=2.558)
Awards
1. The 11th Chinese Young Women in Science Fellowship (2015), All-China Women's Federation, China Association for Science and Technology, National Commission of the People's Republic of China for UNESCO, and L'Oreal China.
2. The Distinguished Professor of “Pearl River Scholar”(2014)， Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme.
3. The leading Talents of Scientific & Technological Innovation (2014), Ministry of Science and Technology, China.
4. The National Science Fund for Distinguished Young Scholars (2013), National Natural Science Foundation of China.
5. New Century Excellent Talent in University of China (2009), Ministry of Education of China.
6. Second Class Prize for Natural Science Achievement (2005).
