学术简历

1999-2004年就读于郑州大学bbin平台 ，获医学学士学位；

2004-2010年就读于bbin平台-bbin官网-bbin电子 ，获医学硕士和博士学位；

2011-2013年在中山大学中山医学院做博士后研究；

2013年受聘于bbin平台-bbin官网-bbin电子 任讲师；

2017年被聘为副教授；

2017-2018年美国杜克大学访问学者。

    致力于传染病流行病学方面的研究，入选2015年广州市“珠江科技新星专项”人才支持项目；主持国家自然科学基金青年项目1项，中国博士后基金1项，广东省自然科学基金1项，广东省科技计划1项，指导学生国家大学生创新训练计划项目4项；参与“十二五”“十三五”国家传染病防治科技重大专项2项，国家自然科学基金4项。在国内外杂志发表论文81篇，以第一作者或通讯作者在Emerg Microbes Infect，Scientific reports,Epidemiology and Infection、International Journal of Infectious Diseases等杂志发表论著41篇，参与获得发明专利3项，作为主编参编专著1部。近年来的主要研究方向是：传染病流行规律及干预研究，传染病疫苗研发和评价。

社会兼职

1. 国际传染病协会会员

2. 广东省预防医学会流行病学专业委员会青年委员会常务委员

3. 广东省预防医学会社会医学与公共卫生专业委员会常务委员

4. 全国公共卫生与预防医学名词编写委员会流行病学名词编写分委会委员

5. 广东省新冠病毒疫苗预防接种异常反应调查诊断专家组专家


主要承担或参与的课题

  • 国家自然科学基金青年基金. 海洋源性NA和NF-кB双靶向抗流感新型先导化合物研究. 81201283. 23万. 2013.1-2015.12. 主持
  • 广东省基础与应用基础研究基金自然科学基金，省级科研项目, 2022A1515011012, 新冠疫苗有效性的预测评价体系建立, 2022.01-2024.12.31. 10万元, 在研, 主持
  • 2019-nCoV感染危险因素及感染传播途径研究，佛山市“新型冠状病毒感染的肺炎”应急科技攻关专项（2020001000430）200万. (2020.6-2022.6) (Co-PI)
  • 中国博士后科学基金. 海洋源性神经氨酸酶抑制剂类化合物VD3抗流感病毒分子机制研究. 20110490954. 3万. 2011.4-2013.3. 主持
  • 广州市科技计划-珠江科技新星专项. EV71手足口病重症病例的危险因素及预测模型研究. 201506010072. 30万. 2015.1.1-2017.12.31. 主持.
  • 广东省省级科技计划. Global Health理念下广东居民传染病防控知识普及研究. 2017A070713013.10万.2017.1.1-2018.12.31.支持.
  • 广州市科学技术协会-科普合作与交流工程专项. 广东在全球突发传染病发生中的作用及公众预防措施科技普及研究. K2016070302. 2万. 2016.1-2016.12. 主持
  • 横向-浙江大学. 传染病信息平台广东示范区数据清洗复核分析.5万. 2015.1-2015.12.主持
  • 国家“十一五”艾滋病和病毒性肝炎等重大传染病科技专项. 广东省传染病病原谱流行规律研究. 2009ZX10004213. 1539万. 2009.1-2011.12. 主要执行人之一
  • 国家“十二五”艾滋病和病毒性肝炎等重大传染病科技专项. 广东省传染病病原谱流行规律研究. 2012ZX10004213. 1570.17万. 2012.1-2015.12. 主要执行人之一
  • “十二五”国家科技重大专项. 广东艾滋病、病毒性肝炎社区综合防治研究. 2012ZX10004-902. 2425.77万. 2012.1-2015.12.主要执行者之一。主要负责生物样本库的建设、各家合作单位联系协调及各种项目材料的撰写工作。
  • “十三五”国家科技重大专项. 广东艾滋病、病毒性肝炎和结核病社区综合防治研究. 2018ZX10004-902. 2425.77万. 2018.1-2020.12.主要执行者之一。主要负责生物样本库的建设、各家合作单位联系协调及各种项目材料的撰写工作。
  • 国家自然科学基金面上项目. 基于病毒样颗粒技术的基孔肯雅病毒感染免疫机制研究. 81373050. 60万. 2014.1-2017.12. 参与
  • 国家自然科学基金面上项目. 基于One Health理念建立动物职业暴露人群流感监测体系的研究. 81473034. 60万. 2015.1-2018.12. 参与
  • 国家自然科学基金面上项目. 手足口病气象、社会经济和人口学危险因素研究.81473064. 70万. 2015.1-2018.12. 参与

 

以第一作者或通讯作者发表文章

  1. Jiayi Zhong, Qianhong Zhong, Husheng Xiong, Dawei Wu, Caiyun Zheng, Shuang Liu, Qinyi Zhong, Yan Chen, Dingmei Zhang. Public acceptance of COVID-19 control measures and associated factors during Omicron-dominant period in China: a cross-sectional survey. BMC Public Health (2024) 24:543.
  2. Shuang Liu*, Ping Wang*, Xiaolu Shi*, Tingsong Weng, Jiayi Zhong, Xiaomin Zhang, Jing Qu, Long Chen, Qing Xu, Xiang Meng, Husheng Xiong, Dawei Wu, Dajun Fang#, Bo Peng#, Dingmei Zhang#. Maternal antibody transfer rate of vaccination against SARS-CoV-2 before or during early pregnancy and its protective effectiveness on offspring. J Med Virol. 2023;95:e29125.
  3. Yajuan Zhu*, Husheng Xiong*, Shuang Liu, Dawei Wu, Xiaomin Zhang, Xiaolu Shi , Jing Qu, Long Chen, Zheng Liu, Bo Peng#, Dingmei Zhang#. Combining MOE Bioinformatics Analysis and In Vitro Pseudovirus Neutralization Assays to Predict the Neutralizing Ability of CV30 Monoclonal Antibody on SARS-CoV-2 Variants. Viruses. 2023 Jul; 15(7): 1565.
  4. Zhu, Y.; Zhong, Q.; Ma, Z.; Liu, S.; Lan, Y.; Peng, B.; Zhang, X.; Shi, X.; Qu, J.;Wu, Z.; Zhimeng Zhao, Xilin Zhang, Dingmei Zhang. Neutralization Effect of Sera against Delta and Omicron in Patients Recovering from COVID-19 and Inactivated Vaccine Recipients. Vaccines 2023, 11, 471. 
  5. Jiayi Zhong; Wen Wang; Shuang Liu; Yifei Chen; Husheng Xiong; Xiang Meng; Dingmei Zhang; Yu Ma; Effectiveness of Matermallnactivated COvlD-19Vaccination against Omicron lnfection in infants during the First 12 Months of Life: A Test-Negative Case-Control Study, Vaccines,2023, 11(9): 1402.
  6. Zhang, D.; Zhong, J.; Xiong, H.; Li, Y.; Guo, T.; Peng, B.; Fang, C.; Kang, Y.; Tan, J.; Ma, Y. Protective Effect of Inactivated COVID-19 Vaccines against Omicron BA.2 Infection in Guangzhou: A Test-Negative Case-Control Real-World Study. Vaccines 2023, 11, 566. 
  7. Yufen Li, Tong Guo, Jiayi Zhong, Chuanjun Fang, Husheng Xiong, Zengyun Hu, Yajuan Zhu, Jinlin Tan, Shuang Liu, Qinlong Jing, Dingmei Zhang. Effect of Vaccination Time Intervals on SARS-COV-2 Omicron Variant Strain Infection in Guangzhou: A Real-World Matched Case-Control Study. Vaccines (Basel) 2022 Nov 1;10(11):1855.
  8. Lin Gan, Yan Chen, Jinlin Tan, Xuezhi Wang, Dingmei Zhang. Does potential antibody-dependent enhancement occur during SARS-CoV-2 infection after natural infection or vaccination? A meta-analysis. BMC Infect Dis. 2022 Sep 19;22(1):742. 
  9. Jinlin Tan, Zhilong Wu, Lin Gan, Qianhong Zhong, Yajuan Zhu, Yufen Li, Dingmei Zhang. Impact of Vaccination and Control Measures on the Fatality of COVID‑19: An Ecological Study. J Epidemiol Glob Health. 2022 Sep 26;1-16.
  10. Tan, J.; Wu, Z.; Hu, P.; Gan, L.; Wang, Y.; Zhang, D*. Association between Mutations in Papain-like Protease (PLpro) of SARS-CoV-2 with COVID-19 Clinical Outcomes. Pathogens 2022, 11, 1008. 
  11. Zhu, Y.; Liu, S.; Zhang, D*. Effectiveness of COVID-19 Vaccine Booster Shot Compared with Non-Booster: A Meta-Analysis. Vaccines 2022, 10, 1396. 
  12. Hongchun Du, Yajuan Zhu, Yan Chen, Shidan Zhou, Jiani Tong, Yingnan Deng, Dingmei Zhang*. Surveillance system-based physician reporting of pneumonia of unknown etiology in China: A cross-sectional study. Asian Pacific Journal of Tropical Medicine 2022; 15(4): 153-160.
  13. Shuang Liu, Jiayi Zhong and Dingmei Zhang*. Transplacental Transfer of Maternal Antibody against SARS-CoV-2 and Its Influencing Factors: A Review. Vaccines 2022, 10, 1083. 
  14. Xiao-Ning Li, Yong Huang, Wen Wang, Qin-Long Jing , Chun-Huan Zhang , Peng-Zhe Qin , Wei-Jie Guan, Lin Gan, Yi-Lan Li , Wen-Hui Liu, Hang Dong, Yu-Tian Miao, Shu-Jun Fan, Zhou-Bin Zhang*, Ding-Mei Zhang*, Nan-Shan Zhong*. Effectiveness of inactivated SARS-CoV-2 vaccines against the Delta variant infection in Guangzhou: a test-negative case-control real-world study. Emerg Microbes Infect. 2021 Dec;10(1):1751-1759.
  15. Liu J, Chen Y, Hu P, Gan L, Tan QM, Huang XQ, Ma ZZ, Lin CJ, Wu DW, Zhu X, Zhang DM*. Caregivers: the potential infection resources for the sustaining epidemic of hand, foot, and mouth disease/herpangina in Guangdong, China?[J]. Archives of Public Health.  2021 Apr 23;79(1): 54.
  16. Gan L, Chen Y, Hu P, Wu D, Zhu Y, Tan J, Li Y, Zhang D. Willingness to Receive SARS-CoV-2 Vaccination and Associated Factors among Chinese Adults: A Cross Sectional Survey[J]. International Journal of Environmental Research and Public Health,2021,18(4):1993.
  17. Hu P, Ma M, Jing Q, Ma Y, Gan L, Chen Y, Liu J, Wang D, Zhang Z, Zhang D. Retrospective study identifies infection related risk factors in close contacts during COVID-19 epidemic[J]. International Journal of Infectious Diseases,2021,103:395-401.
  18. Peipei Hu , Jundi Liu , Lin Gan, Yan Chen, Kaiyi Su, Yuxing Chen, Dingmei Zhang. Lack of Effective Home Quarantine: The Cause of the Continuing Prevalence of Hand, Foot, and Mouth Disease in China? J Infect Public Health. 2020 May 27;S1876-0341(20)30477-9.
  19. Hu P, Liu J, Zhang D. Association of NTCP Gene Polymorphisms and Spontaneous Clearance of Hepatitis B Virus in Asia: A Meta-Analysis[J]. Hepatitis Monthly,2019,19(9): e94500.
  20. Liu J, Deng Y, Jing Q, Chen X, Du Z, Liang T, Yang Z, Zhang D, Hao Y. Dengue Infection Spectrum in Guangzhou: A Cross-Sectional Seroepidemiology Study among Community Residents between 2013 and 2015. Int J Environ Res Public Health. 2018 Jun 11;15(6). pii: E1227.
  21. Jundi Liu, Xiaolu Tian, Yu Deng, Zhicheng Du, Tianzhu Liang, Yuantao Hao and Dingmei Zhang. Risk Factors Associated with Dengue Virus Infection in Guangdong Province: A Community-Based Case-Control Study. Int. J. Environ. Res. Public Health 2019, 16, 617.
  22. Dingmei Zhang. A template for EV-A71 vaccine evaluation in the real world. Lancet Child Adolesc Health. 2019 Jul 30. pii: S2352-4642(19)30181-6.
  23. Dingmei Zhang, Yan Chen, Xiashi Chen, Zhenjian He, Xun Zhu, Yuantao Hao. Enterovirus 71 Neutralizing Antibodies Seroepidemiological Research among Children in Guangzhou, China between 2014 and 2015: A Cross-Sectional Study. Int. J. Environ. Res. Public Health 2017, Mar 20, 14(3), 319.
  24. Dingmei Zhang, Ruolin Li, Wangjian Zhang, Guowei Li, Zhanzhong Ma, Xiashi Chen, Zhicheng Du, Zhiyuan Li, Pi Guo, Zhuochen Lin, Jiahai Lu, Yuantao Hao. A Case-control Study on Risk Factors for Severe Hand, Foot and Mouth Disease. Scientific Reports. 2017 Jan 13;7:40282. 
  25. Zhicheng Du, Wangjian Zhang, Dingmei Zhang, Shicheng Yu, Yuantao Hao. The threshold effects of meteorological factors on Hand, foot, and mouth disease (HFMD) in China, 2011. Scientific Reports. 2016 Nov 16;6: 36351.
  26. Pengyuan Li, Tao Li, Qiuyun Gu, Xiaomin Chen, Jiahui Li, Xiashi Chen, Yan Chen, Danwei Zhang, Rong Gao, Zhenjian He, Xun Zhu, Wangjian Zhang, Yuantao Hao, Dingmei Zhang. Children’s Caregivers and Public Playgrounds: Potential Reservoirs of Infection of Hand-foot-and mouth Disease. Scientific Reports. 2016 Nov 7;6:36375.
  27. Haogao Gu, Ross Ka-Kit Leung, Qinlong Jing, Wangjian Zhang, Zhicong Yang, Jiahai Lu, Yuantao Hao, Dingmei Zhang. Meteorological Factors for Dengue Fever Control and Prevention in South China. Int J Environ Res Public Health. 2016, Aug 31; 13(9), 867.
  28. Dingmei Zhang, Zhiyuan Li, Wangjian Zhang, Pi Guo, Zhanzhong Ma, Qian Chen, Shaokun Du, Jing Peng, Yu Deng and Yuantao Hao. Hand-Washing: The Main Strategy for Avoiding Hand, Foot and Mouth Disease. Int J Environ Res Public Health. 2016 Jun 18;13(6). pii: E610.
  29. Dingmei Zhang*, Mengmeng Ma*, Weitao Wen*, Xun Zhu, Lin Xu, Zhenjian He, Xia He, Jueheng Wu, Yiwen Hu, Yun Zheng, Yu Deng,  Cuiji Lin, Jiahai Lu, Mengfeng Li, Kaiyuan Cao. Clinical epidemiology and molecular profiling of human bocavirus in faecal samples from children with diarrhoea in Guangzhou, China. Epidemiology and Infection. 2015 Aug;143(11):2315-29.
  30. Dingmei Zhang*, Zhenjian He*, Lin Xu*, Xun Zhu, Jueheng Wu, Weitao Wen, Yun Zheng, Yu Deng, Jieling Chen, Yiwen Hu, Mengfeng Li, Kaiyuan Cao. Epidemiology characteristics of respiratory viruses found in children and adults with respiratory tract infections in Southern China. International Journal of Infectious Diseases, 2014,Aug;25:159-64. doi: 10.1016/j.ijid.2014.02.019.
  31. Jing Peng, Dingmei Zhang#, Yu Ma, Guoling Wang, Zhongmin Guo, Jiahai Lu#. Protective effect of fluvastatin on influenza virus infection. Molecular Medicine Reports. 2014 Jun;9(6):2221-6.
  32. Lin Xu*, Xia He*, Dingmei Zhang*, Zhu Wang, Fashen Feng, Yang Wang, Mengfeng Li, Kaiyuan Cao. Surveillance and gene analysis of Human Bocavirus in patients with respiratory infection in Guangzhou, China. Plos One, 2012;7(9):e44876.
  33. Dingmei Zhang, Jiahai Lu. Enterovirus 71 (EV71) vaccine: close but still far. International Journal of Infectious Diseases, 2010, 14(9):e739-43.
  34. Dingmei Zhang, Jiahai Lu, Nanshan Zhong. Pathogenesis of severe acute respiratory syndrome. Chinese medical journal 2008, 121(17):1722-1731.
  35. Dingmei Zhang, Guoling Wang, Jiahai Lu. Severe acute respiratory syndrome: vaccine on the way. Chinese medical journal 2005, 118(17):1468-1476. 
  36. Jiahai Lu*, Dingmei Zhang*, Guoling Wang*, Zhongmin Guo*, Bingyan Tan, Liping Ouyang, Li Lin, Yimin Liu, Weiqing Chen, Wenhua Ling, Xinbing Yu, Nanshan Zhong. Variation analysis of the severe acute respiratory syndrome coronavirus putative non-structural protein 2 gene and construction of three-dimensional model. Chinese medical journal 2005, 118(9):707-713.
  37. Jiahai Lu*, Dingmei Zhang*, Guoling Wang*, Zhongmin Guo*, Juan Li*, Bingyan Tan, Liping Ou-Yang, Wenhua Ling, Xinbing Yu, Nanshan Zhong. Sequence analysis and structural prediction of the severe acute respiratory syndrome coronavirus nsp5. Acta biochimica biophysica Sinica 2005, 37(7):473-479.
  38. 张定梅，朱勋，姚婷婷，徐霖，吴珏珩，何振健，郑芸，曹开源. 广东省2009-2012年呼吸道合胞病毒的流行病学特征.中山大学学报（医学科学版）2013.3.34(2):292-8
  39. 李鹏媛，徐浩，顾豪高，马蒙蒙，陆家海，郝元涛，张定梅. 中国大陆H7N9禽流感病毒流行病学特征及血凝素和神经氨酸酶的分子进化研究. 中山大学学报（医学科学版）. 2014.11.35(6):932-940.
  40. 顾豪高，张王剑，徐浩，李鹏媛，吴洛林，郭貔，郝元涛，陆家海，张定梅. 中国人感染H7N9 禽流感危险区域预警识别的研究. 中华流行病学杂志. 2015, 36 (5): 470-475. 
  41. 李鹏媛，刘佑琼，张定梅.埃博拉病毒及埃博拉出血热. 中国预防医学杂志. 2015,16(8):632-637.

 

参编教材：

1.《影响人类健康的常见人兽共患病》，中山大学出版社，2009年，副主编

2.《悄然的拜访者-大众传染病防控》，中山大学出版社，2019年，主编