个人简历 [Biography]

林华亮，教授、博导，担任院长助理、流行病学系主任、教育部环境与健康国际合作联合实验室副主任。先后获得中山大学“百人计划”中青年杰出人才、广东省杰出青年医学人才等称号，入选“全球顶尖前10万科学家排名榜”和全球前2%顶尖科学家榜单。长期从事环境因素及其与基因易感性交互作用在慢性病发生发展中的作用和机制研究，并提出了制定大气污染控制浓度阈值的新方法。主持国家重点研发计划项目课题1项、国家自然科学基金4项、广东省科技厅项目3项。担任Cardiac and Cardiovascular Research、Environment International、Journal of Gerontology: Medical Sciences和The Innovation杂志编委。发表SCI文章100余篇，包括在Lancet Public Health、Journal of Hepatology、Environmental Health Perspectives、American Journal of Epidemiology、The Innovation、EClinicalMedicine、Lancet Regional Health - Western Pacific、PLOS Medicine、BMC Medicine、Journal of Allergy & Clinical Immunology、Neurology、Brain、Thorax等国际权威期刊上第一/通讯作者80余篇；5篇为ESI高被引论文(Top1%)，文章被引用超过13000次，H-Index达到50。获得国家发明专利授权1项。主编中文专著4部、英文专著1部。

 

 

Hualiang Lin, Professor, Assistant Dean and Chair of Department of Epidemiology, School of Public Health, Sun Yat-sen University. He has granted Outstanding Young and Middle-aged Talents of Sun Yat-sen University's "One Hundred People Program" and Outstanding Young Medical Talents in Guangdong Province, and has been ranked as "Global Top 100,000 Scientists" and the World's Top 2% Scientists. His research focuses on the role and mechanism of environmental factors and their interaction with genetic susceptibility in the development of chronic diseases, and proposed a new method for formulating the concentration threshold of atmospheric pollution control. As the PI, he has been funded by the National Key Research and Development Plan, four projects of the National Natural Science Foundation, and three projects of Guangdong Science and Technology Department. He serves as the editorial board member of Cardiac and Cardiovascular Research, Environment International, Journal of Gerontology: Medical Sciences and The Innovation. He has published more than 100 articles, such as Lancet Public Health, Journal of Hepatology, EHP, American Journal of Epidemiology, The Innovation, EClinicalMedicine, Lancet Regional Health - Western Pacific, PLOS Medicine, BMC Medicine, Journal of Allergy & Clinical Immunology, Neurology, Brain and Thorax; eight articles are ESI Highly Cited Papers (Top1%). His study has been cited for more than 13,000 times with an H-Index of 50. He also published, as one chief editor, four monographs.


学习经历 [Education]

  • 博士，香港中文大学赛马会公共卫生及基层医疗学院，公共卫生

PhD, JC School of Public Health and Primary Care, The Chinese University of Hong Kong

  • 硕士，中国疾病预防控制中心，流行病与卫生统计学

Master in Epidemiology and Medical Statistics, Chinese Center for Disease Control and Prevention, China

  • 学士，山东大学bbin平台 ，预防医学

Bachelor in Preventive Medicine, School of Public Health, Shandong University, China

 

工作经历 [Employment]

  • 2021.02-至今，bbin平台-bbin官网-bbin电子 , 教授、博士生导师；

2021.02-, Professor, School of Public Health, Sun Yat-sen University;

  • 2017.11-2021.02，bbin平台-bbin官网-bbin电子 , 副教授、博士生导师；

2017.11-2021.02, Associate Professor, School of Public Health, Sun Yat-sen University;

  • 2015.12-2016.12，美国圣路易斯大学，访问学者；

2015.12-2016.12, Visiting scholar, Saint Louis University, US;

  • 2012.11-2017.11，广东省公共卫生研究院，环境与健康研究室负责人, 副主任医师；

2012.11-2017.11, Director of Division of Environmental and Health, Guangdong Provincial Institute of Public Health;

  • 2011.10-2012.10，香港中文大学赛马会公共卫生及基层医疗学院, 博士后；

2011.10-2012.10, Postdoctoral fellow, JC School of Public Health and Primary Care, The Chinese University of Hong Kong;

  • 2007.07-2008.09，深圳出入境检验检疫局, 国际旅行卫生保健中心

2007.07-2008.09, International Travel Health Care Center, Shenzhen Entry Exit Inspection and Quarantine Bureau, China


社会兼职 [Memberships]

  • 中华预防医学会流行病学委员会 委员

Committee Member, Epidemiology Branch of Chinese Preventive Medicine Association

  • 中华预防医学会环境卫生学委员会 委员

Committee Member, Environmental Health Branch of Chinese Preventive Medicine Association

  • 中华预防医学会残疾预防与控制委员会 委员

Committee Member, Specialist Committee of Disability Prevention and Control of Chinese Preventive Medicine Association

  • 中国初级卫生保健基金会医学统计专业委员会 常务委员

Standing Committee, Specialist Committee of Medical Statistics of Primary Health Care Foundation of China

  • 中华预防医学会媒介生物学及控制委员会 委员

Committee Member, Vector Biology and Control Branch of Chinese Preventive Medicine Association

  • 广东省精准医学应用学会脑卒中分会 副主任委员

Deputy Director, Stroke Branch of Guangdong Precision Medicine Application Association

  • 广东省精准医学应用学会头痛分会 副主任委员

Deputy Director, Headache Branch of Guangdong Precision Medicine Application Association

  • 广东省预防医学会流行病学青年委员会 副主任委员

Deputy Director, the Youth Committee on Epidemiology of Guangdong Preventive Medicine Association

  • Cardiac and Cardiovascular Research杂志 编委

Member of the Editorial Board, Cardiac and Cardiovascular Research

  • Environment International 杂志 编委

Member of the Editorial Board, Environment International

  • Journal of Gerontology: Medical Sciences杂志 编委

Member of the Editorial Board, Journal of Gerontology: Medical Sciences

  • The Innovation杂志 编委

Member of the Editorial Board, The Innovation

  • Future杂志 编委

Member of the Editorial Board, Future

  • BMC Public Health杂志 副主编

Associate Editor, BMC Public Health

  • 华南预防医学杂志编委

Member of the Editorial Board, South China Journal of Preventive Medicine

 

承担或参与的主要课题 [Research projects]

    1. 国家重点研发计划课题，2022YFC2305305,整合病原基因组和多源异构环境数据的急性传染病预警模型研究，2022/12-2025/11,课题负责人；

State Key Research and Development Program of China (2022YFC2305305), Research on the early warning model of acute infectious diseases integrating pathogenic genome and multi-source heterogeneous environmental data. 2022/12-2025/11, PI2

    2.国家自然科学基金面上项目，81972993，孕期细颗粒物暴露对新生儿早产风险的影响及胎盘外泌体介导的miRNA-21和miRNA-200a对其调控机制研究，2020/01–2023/12，主持;

National Natural Science Foundation of China (81972993) Research on the effect of exposure to fine particles during pregnancy on the risk of premature birth in newborns and the regulatory mechanism of miRNA-21 and miRNA-200a mediated by placental exocrine. 2020/01–2023/12, PI.

   3. 国家自然科学基金新冠肺炎专项项目，82041021，人口流动及其干预措施对新冠肺炎在湖北省内和跨省传播的驱动作用、机制和影响因素研究，2020/03–2022/03，主持;

National Natural Science Foundation of China (82041021) Research on the driving role, mechanism and influencing factors of population flow and its intervention measures on the spread of COVID-19 in Hubei Province and across provinces. 2020/03–2022/03, PI.

   4. 国家自然科学基金面上项目，82373534 ，血清miR-200a-SLC7A11介导细胞铁死亡在大气黑碳致脑卒中发病中的作用及机制研究，2024/01–2027/12，主持;

National Natural Science Foundation of China (82373534 ), Study on the role and mechanism of cell iron death mediated by serum miR-200a-SLC7A11 in the incidence of cerebral stroke caused by atmospheric black carbon. 2024/01–2027/12, PI.

   5. 比尔及梅琳达·盖茨基金会项目，社会环境因素对呼吸系统疾病时空传播的影响及其机制研究，2020-2022，主持；

Bill & Melinda Gates Foundation, Research on the influence of social and environmental factors on the space-time transmission of respiratory diseases and its mechanism. 2020-2022, PI.

   6. 中央高校青年教师重点培育项目，19ykzd16，孕期空气污染暴露与早产的流行病学和机制研究，2019/01–2021/12，主持;

Key training projects for young teachers in central colleges and universities (19ykzd16), Epidemiological and mechanism research on the relationship between air pollution exposure during pregnancy and premature birth. 2019/01–2021/12, PI.

    7. 广东省自然科学基金面上项目，孕期臭氧暴露对新生儿早产发生风险的影响及其机制研究，2022-2024，主持；

Natural Science Foundation of Guangdong Province, Research on the impact of ozone exposure during pregnancy on the risk of premature birth in newborns and its mechanism. 2022-2024, PI.

   8. 广东省自然科学基金面上项目，炎症通路在孕期大气污染物暴露致新生儿早产发生风险中的影响及机制研究，2024-2026，主持；

Natural Science Foundation of Guangdong Province, Research on the influence and mechanism of inflammatory pathways on the risk of premature birth of newborns due to exposure to atmospheric pollutants during pregnancy. 2024-2026, PI.

   9. 广东省科技厅“海外名师”团队项目，基于人群健康效应分析的粤港地区大气环境质量标准制修订，2021/09–2023/08，主持;

Science and Technology Planning Project of Guangdong, Revision of the atmospheric environmental quality standard system in Guangdong and Hong Kong based on the analysis of population health effects. 2021/09–2023/08, PI.

   10. 国家自然科学基金青年项目，81202176，宣威市肺癌的时空演变及其影响因素研究，2013/01–2015/12，主持;

National Natural Science Foundation of China (81202176), Research on the space-time evolution of lung cancer in Xuanwei City and its influencing factors. 2013/01–2015/12, PI.

   11. 国家科技部重点研发计划，气候变化健康风险评估、早期信号捕捉及应对策略研究，2018-2023，课题一项目骨干。

State Key Research and Development Program of China, Research on health risk assessment, early signal capture and coping strategies related to climate change. 2018-2023, participation.

   12. 国家自然科学基金面上基金项目，81273139，粤港两地登革热暴发媒介伊蚊密度阈值研究，2013/01–2016/12，参与;

National Natural Science Foundation of China (81273139) Research on the density threshold of Aedes mosquitoes, the medium of dengue fever outbreak in Guangdong and Hong Kong. 2013/01–2016/12, participation.

   13. 国家自然科学基金面上基金项目，30771873，我国登革热的风险评估研究，2008/01–2008/12，参与。

National Natural Science Foundation of China (30771873), Research on the risk assessment of dengue fever in China. 2008/01–2008/12, participation.

 

代表文章 (*通讯作者) [Publications (*Corresponding author)] 

  1.   Ran S, Zhang J, Tian F, Qian Z, Wei S, Wang Y, Chen G, Zhang J, Arnold LD, McMillin SE, Lin HL*. Association of metabolic signatures of air pollution with MASLD: Observational and Mendelian randomization study. Journal of Hepatology, 2024, doi.org/10.1016/j.jhep.2024.09.033.
  2. Chen G, Qian ZM, Zhang J, Wang X, Zhang Z, Cai M, Arnold LD, Abresch C, Wang C, Liu Y, Fan Q, Lin HL*. Associations between Changes in Exposure to Air Pollutants due to Relocation and the Incidence of 14 Major Disease Categories and All-Cause Mortality: A Natural Experiment Study. Environmental Health Perspectives. 2024;132(9):97012.
  3. Zhuo B, Ran S, Qian AM, Zhang J, Tabet M, Howard SW, Zhang Z, Tian F, Lin HL*. Air Pollution Metabolomic Signatures and Chronic Respiratory Diseases Risk: A Longitudinal Study. Chest. 2024, S0012-3692(24):04843-04848.
  4. Qi J, Ruan Z, Qian ZM, Yin P, Yang Y, Acharya BK, Wang L, Lin HL*, Potential gains in life expectancy by attaining daily ambient fine particulate matter pollution standards in mainland China: A modeling study based on nationwide data. PLOS Medicine, 2020, 17(1):e1003027 (ESI高被引论文，ESI Highly Cited Paper).
  5. Ma Q, Li R, Wang L, Yin P, Wang Y, Yan C, Ren Y, Qian ZM, Vaughn MG, McMillin SE, Hay SI, Naghavi M, Cai M, Wang C, Zhang Z, Zhou M*, Lin HL*, Yang Y*. Temporal trend and attributable risk factors of stroke burden in China, 1990-2019: An analysis for the Global Burden of Disease study 2019. The Lancet Public Health. 2021, 6 (12): e897-e906 (ESI高被引和热点论文，ESI Highly Cited Paper and Hot Paper).
  6. Zhang Z, Chen L, Wang X, Wang C, Yang Y, Li H, Cai M, Lin HL*. Associations of Air Pollution and Genetic Risk With Incident Dementia: A Prospective Cohort Study. American Journal of Epidemiology. 2023;192(2):182-94.
  7. Zhang J, Chen G, Xia H, Wang X, Wang C, Cai M, Gao Y, Lip GYH, Lin HL*. Associations of Life’s Essential 8 and fine particulate matter pollution with the incidence of atrial fibrillation. Journal of Hazardous Materials. 2023; 459: 132114.
  8. Wang X, Guo Y, Cai M, Qian Z, Zhang S, Zhang Z, Yang Y, Vaughn MG, Aaron HE, Wu F, Zhang Y, Lin HL*. Constituents of fine particulate matter and asthma in six low- and middle-income countries. Journal of Allergy and Clinical Immunology. 2022. 150: 214-222.
  9. Cai M, Zhang S, Lin X, Qian Z, McMillin SE, Yang Y, Zhang Z, Pan J, Lin HL*, Association of Ambient Particulate Matter Pollution of Different Sizes with In-Hospital Case Fatality Among Stroke Patients in China. Neurology, 2022. 98(24): e2474-e2486 (ESI高被引论文，ESI Highly Cited Paper).
  10. Cai M, Lin X, Wang X, Zhang S, Wang C, Zhang Z, Pan J, Lin HL*, Long-term exposure to ambient fine particulate matter chemical composition and in-hospital case fatality among patients with stroke in China. Lancet Regional Health - Western Pacific 2023:100679 (ESI高被引论文，ESI Highly Cited Paper).
  11. Zhang S, Qian Zhengmin M, Chen L, Zhao X, Cai M, Wang C, Zou H, Wu Y, Zhang Z, Li H, Lin HL*. Exposure to Air Pollution during Pre-Hypertension and Subsequent Hypertension, Cardiovascular Disease, and Death: A Trajectory Analysis of the UK Biobank Cohort. Environmental Health Perspectives. 2023;131(1):017008 (ESI高被引论文，ESI Highly Cited Paper).
  12. Cai M, Li H, Wu Y, Zhang S, Wang X, Zhang Z, Lin HL*, Ambient Air Pollution Associated with Body Fat Percentages at Different Body Compartments: A Cohort Study of UK Biobank Participants. Environmental Health Perspectives, 2022. 130(6): 067702.
  13. Chen L, Cai M, Li H, Wang X, Tian F, Wu Y, Zhang Z, Lin HL*, Risk/benefit tradeoff of habitual physical activity and air pollution on chronic pulmonary obstructive disease: findings from a large prospective cohort study. BMC Medicine, 2022. 20(1): 70 (ESI高被引论文，ESI Highly Cited Paper).
  14. Tian F, Cai M, Li H, Qian Z, Chen L, Zou H, Zhang Z, Wang C, Xian H, McMillin SE, Lin HL*. Air Pollution Associated With Incident Stroke, Poststroke Cardiovascular Events, and Death: A Trajectory Analysis of a Prospective Cohort. Neurology. 2022;99(22):e2474-e2484.
  15. Cao D, Li D, Wu Y, Qian ZM, Liu Y, Liu Q, Sun J, Guo Y, Zhang S, Jiao G, Yang X, Wang C, McMillin SE, Zhang X, Lin HL*. Ambient PM2.5 exposure and hospital cost and length of hospital stay for respiratory diseases in 11 cities in Shanxi Province, China. Thorax, 2021, 76:815–820.
  16. Liu K, Ai S, Song S, Zhu G, Tian F, Li H, Gao Y, Wu Y, Zhang S, Shao Z, Liu Q, Lin HL*, Population movement, city closure in Wuhan and geographical expansion of the 2019-nCoV pneumonia infection in China in January 2020. Clinical Infectious Diseases, 2020, 71(16): 2045-2051.
  17. Ruan Z, Qi J, Qian ZM, Zhou M, Yang Y, Zhang S, Vaughn MG, LeBaige MH, Yin P, Lin HL*. Disease burden and attributable risk factors of respiratory infections in China from 1990 to 2019.  Lancet Regional Health - Western Pacific, 2021, 11(2021): 100153.
  18. Wang HL, Sun J, Qian ZM, Gong YQ, Zhong JB, Yang RD, Wan CL, Zhang SQ, Ning DF, Xian H, Chang JJ, Wang CJ, Shacham E, Wang JQ, Lin HL*. Association between Air Pollution and Atopic Dermatitis in Guangzhou, China: Modification by Age and Season. British Journal of Dermatology, 2021, 184(6): 1068-1076.
  19. Zhang Z, Chen L, Qian Z, Li H, Cai M, Wang X, McMillin SE, Vaughn MG, Liu K, Shao Z, Lin HL*. Residential green and blue space associated with lower risk of adult-onset inflammatory bowel disease: Findings from a large prospective cohort study. Environment International. 2022;160: 107084.
  20. Tian F, Liu X, Chao Q, Qian Z, Zhang S, Qi L, Niu Y, Arnold LD, Zhang S, Li H, Lin HL*, Liu QY*. Ambient air pollution and low temperature associated with case fatality of COVID-19: A nationwide retrospective cohort study in China. The Innovation. 2021, 2(3): 100139
  21. Wu R, Ai S, Cai J, Zhang S, Qian Z, Zhang Y, Wu Y, Chen L, Tian F, Li H, Li M, Lin HL*. Predictive model and risk factors for case fatality of COVID-19: a cohort of 21,392 cases in Hubei, China. The Innovation, 2020, 1(2): 100022.
  22. Yang Y, Qi J, Ruan Z, Yin P, Zhang S, Liu J, Liu Y, Li R, Wang L, Lin HL*. Changes in life expectancy of respiratory diseases from attaining daily PM2.5 standard in China: A nationwide observational study. The Innovation, 2020, 1(3): 100064.
  23. Zhang S, Yang Y, Xie X, Li H, Han R, Hou J, Sun J, Qian Z, Wu S, Huang C, Howard SW, Tian F, Deng W, Lin HL*. The effect of temperature on cause-specific mental disorders in three subtropical cities: A case-crossover study in China. Environment International, 2020, 143: 105938.
  24. Tian F, Qi J, Wang L, Yin P, Qian Z, Ruan Z, Liu J, Liu Y, McMillin SE, Wang C, Lin HL*, Zhou M*. Differentiating the effects of ambient fine and coarse particles on mortality from cardiopulmonary diseases: A nationwide multicity study. Environment International, 2020, 145: 106096.
  25. Liang Z, Yang Y, Qian Z, Ruan Z, Chang J, Vaughn MG, Zhao Q, Lin HL*, Ambient PM2.5 and birth outcomes: Estimating the association and attributable risk using a birth cohort study in nine Chinese cities. Environment International, 2019, 126:329-335.
  26. Ruan Z, Qian ZM, Xu Y, Wu J, Kan H, Yang Y, Acharya BK, Jiang C, Syberg KM, Iwelunmor J, Ma W, Lin HL*, Applying the concept of "number needed to treat" to the formulation of daily ambient air quality standards. Chemosphere 2019, 222: 665-670.

 

研究生招生与博士后招聘 [Enrollment and Recruitment]

  • 硕士研究生(方向：流行病学)

Master (Direction: Epidemiology)

  • 博士研究生(方向：流行病学)

Ph.D. (Direction: Epidemiology)

  • 博士后 名额不限(方向：流行病学、环境流行病学或相关学科) 

Postdoctor, Quota: No limitation (Direction: Epidemiology, Environmental Epidemiology or related disciplines)

 

获奖情况 [Awards]

  • 2024年，广东省科技厅科普作品创作大赛优秀指导老师

The Science Popularization and Creation Competition of Guangdong Provincial Department of Science and Technology in 2024, Excellent Instructor

  • 2023、2024年，全国大学生基础医学创新研究暨实验设计论坛金奖、最佳学术奖 优秀指导老师

The National Forum for Undergraduate on Innovation Research & Experimental Design Competition in 2023 & 2024, Excellent Instructor of the Gold Award and Best Academic Award

  • 2023年，中国大学生统计建模大赛研究生组全国二等奖 优秀指导老师

The National College Student Statistical Modeling Competition in 2023, Excellent Instructor of the National Second Prize in postgraduate group

  • 2022年，全国健康科普大赛全国二等奖 优秀指导老师

The National Health Science Popularization Competition in 2022, Excellent Instructor of the National Second Prize

  • 2022年，中国大学生统计建模大赛本科组全国二等奖 优秀指导老师

The National College Student Statistical Modeling Competition in 2022, Excellent Instructor of the National Second Prize in undergraduate group

  • 2022年，广东省大学生统计建模大赛一等奖 优秀指导老师

College Student Statistical Modeling Competition of Guangdong Province in 2022, Excellent Instructor of the First Prize

  • 2017年，中山大学“百人计划”中青年杰出人才

"One Hundred People Plan" of Sun Yat-sen University in 2017, Outstanding young and middle-aged talents

  • 2018年，广东省杰出青年医学人才称号

Outstanding Young Medical Talents in Guangdong Province in 2018