学术简历
学习经历
1999.10 - 2002.5 中山大学肿瘤防治中心临床肿瘤学专业，博士后
1992.9 - 1998.7 中国医学科学院中国协和医科大学流行病学专业，获博士学位
1987.9 - 1992.7 山西医科大学预防医学专业， 获学士学位
工作经历
2006.12至今 中山大学肿瘤防治中心 教授
2002.05 - 2006.12 中山大学肿瘤防治中心 副教授
社会兼职
中国医药生物技术协会组织生物样本库分会副主任委员
中国抗癌协会肿瘤病因学专业委员会常务委员
中国抗癌协会肿瘤流行病学专业委员会委员
广东省青年科学家协会委员
Chinese Journal of Cancer杂志责任编委
《中华预防医学杂志》通讯编委
European Journal of Cancer、PLoS One、BMC Cancer、Cancer Epidemiology等国际期刊审稿专家
主要承担或参与的课题
1. 国家自然科学基金杰出青年科学基金：流行病学（No. 81325018），2014-2017年，320万元，项目负责人
2. 国家自然科学基金重大国际合作研究项目：基于高发家系的新一代全基因组测序技术精确鉴定鼻咽癌致病基因及其功能研究（No.81220108022），2013-2017年，280万元，项目负责人
3. “重大新药创制”科技重大专项子项目：恶性肿瘤临床标本库资源库平台建设（No.2011ZX09307-001-04），2011-2013年，160万元，项目共同负责人
4. 国家973计划：病毒致癌机制与干预的基础研究（No.2011CB504303），2011-2015年，70万元，研究骨干
5. 科技部863计划项目：鼻咽癌分子分型和个体化诊疗技术（No.2012AA02A501），2012-2015年，50万元，分题负责人
6. 美国NIH基金生物样本库负责人：Gene-Environment-EBV Interaction in the Etiology of Nasopharyngeal Carcinoma (No.#R01CA115873-01)，2010-2014年，100万元，项目负责人
近期发表的主要文章
1. Tan DE, Foo JN, Bei JX, Chang J, Peng R, Zheng X, Wei L, Huang Y, Lim WY, Li J, Cui Q, Chew SH, Ebstein RP, Kuperan P, Lim ST, Tao M, Tan SH, Wong A, Wong GC, Tan SY, Ng SB, Zeng YX, Khor CC, Lin D*, Seow AL*, Jia WH*, Liu J*. Genome-wide association study of B cell non-Hodgkin lymphoma identifies 3q27 as a susceptibility locus in the Chinese population. Nat Genet. 2013 Jun 9;45(7):804-7. (IF=29.352)
2. Jia WH*, Zhang B, Matsuo K, Shin A, Xiang YB, Jee SH, Kim DH, Ren Z, Cai Q, Long J, Shi J, Wen W, Yang G, Delahanty RJ; Genetics and Epidemiology of Colorectal Cancer Consortium (GECCO); Colon Cancer Family Registry (CCFR), Ji BT, Pan ZZ, Matsuda F, Gao YT, Oh JH, Ahn YO, Park EJ, Li HL, Park JW, Jo J, Jeong JY, Hosono S, Casey G, Peters U, Shu XO, Zeng YX, Zheng W. Genome-wide association analyses in east Asians identify new susceptibility loci for colorectal cancer. Nat Genet. 2013,45(2):191-6. (IF=29.352)
3. Chen K*, Ma H , Li L , Zang R, Wang C , Song F , Shi T , Yu D, Yang M, Xue W, Dai J, Li S, Zheng H, Wu C, Zhang Y, Wu X, Li D, Xue F,Li H, Jiang Z, Liu J, Liu Y, Li P, Tan W, Han J, Jie J, Hao Q, Hu Z, Lin D, Ma D*, Jia WH*, Shen H*, Wei Q*. Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women. Nat Commun. 2014,5: 4682. (IF=11.47)
4. Xu FH, Xiong D，Xu YF, Cao SM, Xue WQ, Qin HD, Liu WS, Cao JY, Zhang Y, Feng QS, Chen LZ, Li MZ, Liu ZW, Liu Q, Hong MH, Shugart YY, Zeng YX , Zeng MS*, Jia WH*. An epidemiological and molecular study of the relationship between smoking, risk of nasopharyngeal carcinoma, and epstein-barr virus activation. J Natl Cancer Inst. 2012 Sep 19; 104(18):1396-410. (IF=12.583)
5. Jia WH*, Qin HD. Non-viral environmental risk factors for nasopharyngeal carcinoma: A systematic review. Semin Cancer Biol. 2012 Apr;22(2):117-26. (IF=9.33)
6. Qin HD, Shugart YY, Bei JX, Pan QH, Chen L, Feng QS, Chen LZ, Huang W, Liu JJ, Jorgensen TJ, Zeng YX, Jia WH*. Comprehensive pathway-based association study of DNA repair gene variants and the risk of nasopharyngeal carcinoma. Cancer Res. 2011,71(8):3000-8. (IF=9.329)
7. He J, Liao XY, Zhu JH, Xue WQ, Shen GP, Huang SY, Chen W, Jia WH*. Association of MTHFR C677T and A1298C polymorphisms with non-Hodgkin lymphoma susceptibility: evidence from a meta-analysis. Sci Rep. 2014;4: 6159. (IF=5.578)
8. Xue WQ, He YQ, Zhu JH, Ma JQ, He J, Jia WH*. Association of BRCA2 N372H polymorphism with cancer susceptibility: a comprehensive review and meta-analysis. Sci Rep. 2014;4: 6791. (IF=5.578)
9. Xue WQ, Qin HD, Ruan HL, Shugart YY, Jia WH*. Quantitative association of tobacco smoking with the risk of nasopharyngeal carcinoma: A comprehensive meta-analysis of studies conducted between 1979-2011. Am J Epidemiol. 2013 Aug 1;178(3):325-38. (IF=5.23)
10. Shen GP, Pan QH, Hong MH, Qin HD, Xu YF, Chen LZ, Feng QS, Jorgensen TJ, Shugart YY, Zeng YX, Jia WH*. Human genetic variants of homologous recombination repair genes first found to be associated with Epstein-Barr virus antibody titers in healthy Cantonese. Int J Cancer. 2011 Sep 15;129(6):1459-66. (IF=5.085)
11. Ruan HL, Qin HD, Shugart YY, Bei JX, Luo FT, Zeng YX*, Jia WH*. Developing genetic epidemiological models to predict risk for nasopharyngeal carcinoma in high-risk population of China. PLoS One. 2013; 8(2): e56128. doi: 10.1371/ journal.pone. 0056128. (IF=3.234)
12. Ge XS, Ma HJ, Zheng XH, Ruan HL, Liao XY, Xue WQ, Chen YB, Zhang Y, Jia WH*. HOTAIR, a prognostic factor in esophageal squamous cell carcinoma, inhibits WIF-1 expression and activates Wnt pathway. Cancer Sci. 2013 Dec;104(12):1675-82. (IF=3.523)
13. Shen GP, Xu FH, He F, Ruan HL, Cui C, Chen LZ, Zeng YX, Jia WH*. Pretreatment lifestyle behaviors as survival predictors for patients with nasopharyngeal carcinoma. PLoS One. 2012;7(5):e36515. (IF=3.234)
14. He YQ, Zhu JH, Huang SY, Cui Z, He J, Jia WH*. The association between the polymorphisms of TNF-alpha and non-Hodgkin lymphoma: a meta-analysis. Tumour Biol. 2014;35: 12509-17. (IF=3.611)
15. Li Y, Wen ZS, Yang HX, Luo RZ, Zhang Y, Zhang MF, Wang X*, Jia WH*. High expression of Y-Box-Binding protein-1 is associated with poor survival in resectable esophageal squamous Cell carcinoma. Ann Surg Oncol. 2011 Nov;18(12):3370-6. (IF=3.93)
16. Li Y, Yang HX, Luo RZ, Zhang Y, Li M, Wang X*, Jia WH*. High expression of p300 has an unfavorable impact on survival in resectable esophageal squamous cell carcinoma. Ann Thorac Surg. 2011, 91(5):1531-8. (IF=3.849)
17. He J, Wang F, Zhu JH, Chen W, Cui Z, Jia WH*. No association between MTR rs1805087 A > G polymorphism and non-Hodgkin lymphoma susceptibility: evidence from 11 486 subjects. Leuk Lymphoma. 2014: 1-5. (IF=2.891)
18. Li CF, Luo FT, Zeng YX, Jia WH*. Weighted risk score-based multifactor dimensionality reduction to detect gene-gene interactions in nasopharyngeal carcinoma. Int J Mol Sci. 2014;15: 10724-37. (IF=2.862)
19. Zheng XH, Cui C, Ruan HL, Xue WQ, Zhang SD, Hu YZ, Zhou XX, Jia WH*. Plasma microRNA profiling in nasopharyngeal carcinoma patients reveals miR-548q and miR-483-5p as potential biomarkers. Chin J Cancer. 2014;33: 330-8. (IF=2.155)
20. He F, Zou JT, Zhou QF, Niu DL, Jia WH*. Glatiramer acetate reverses cognitive deficits from cranial-irradiated rat by inducing hippocampal neurogenesis. J Neuroimmunol. 2014;271: 1-7.(IF=2.467)
21. Jia WH*, Luo XY, Feng BJ, Ruan HL, Bei JX, Liu WS, Qin HD, Feng QS, Chen LZ, Yao SY, Zeng YX. Traditional Cantonese diet and nasopharyngeal carcinoma risk: a large-scale case-control study in Guangdong, China. BMC Cancer. 2010 Aug 20;10:446. (IF=3.362)
22. He JR, Qin H, Ren ZF*, Cui C, Zhang Y, Ranatunga D, Zeng YX, Jia WH*. MMP-9 expression in peripheral blood mononuclear cells and the association with clinicopathological features and prognosis of nasopharyngeal carcinoma. Clin Chem Lab Med. 2011, 49(4):705-10. (IF=2.707)
23. He JR, Shen GP, Ren ZF*, Qin H, Cui C, Zhang Y, Zeng YX, Jia WH*. Pretreatment levels of peripheral neutrophils and lymphocytes as independent prognostic factors in patients with nasopharyngeal carcinoma. Head Neck. 2012 Feb 9. 2012 Dec;34(12):1769-76. (IF=2.641)
24. Fan Q, He JF, Wang QR, Cai HB, Sun XG, Zhou XX, Qin HD, Shugart YY, Jia WH*. Functional polymorphism in the 5'-UTR of CR2 is associated with susceptibility to nasopharyngeal carcinoma. Oncol Rep. 2013; 30 (1):11-6. (IF=2.301)
25.Ge X, Chen Y, Liao X, Liu D, Li F, Ruan H, Jia WH*. Overexpression of long noncoding RNA PCAT-1 is a novel biomarker of poor prognosis inpatients with colorectal cancer. Med Oncol. 2013 Jun;30(2):588. doi: 10.1007/s12032-013-0588-6. (IF=2.058)
26. Li Y, Yu H, Luo RZ, Zhang Y, Zhang MF, Wang X*, Jia WH*. Elevated expression of Rad51 is correlated with decreased survival in resectable esophageal squamous cell carcinoma. J Surg Oncol. 2011 Nov 1;104(6):617-22. (IF=2.843)
27. Qin HD, Jia WH*, Zhang LL, Liu N, Zhou XX, Wang MH, Feng QS, Chen LZ, Zhang Y, Jorgensen TJ, Zeng YX, Shugart YY*. Elevated Epstein-Barr virus seroreactivity among unaffected members of families with nasopharyngeal carcinoma. J Med Virol. 2011 Oct;83(10):1792-8. (IF=2.217)
28. Xu YF, Liu WL, Dong JQ, Liu WS, Feng QS, Chen LZ, Zeng YX, Zeng MS, Jia WH*. Sequencing of DC-SIGN promoter indicates an association between promoter variation and risk of nasopharyngeal carcinoma in cantonese. BMC Med Genet. 2010 Nov 11;11:161. (IF=2.45)
29. Ren ZF, Liu WS, Qin HD, Xu YF, Yu DD, Feng QS, Chen LZ, Shu XO, Zeng YX, Jia WH*. Effect of family history of cancers and environmental factors on risk of nasopharyngeal carcinoma in Guangdong, China. Cancer Epidemiol. 2010 Aug;34(4):419-24. (IF=2.558)
研究生培养情况
招生专业
流行病与卫生统计学、肿瘤学、分子医学
获奖情况
2015年第11届“中国青年女科学家奖”
2014年广东省“珠江学者”
2014年科技部“科技创新领军人才”入选者
2013年度国家自然科学基金杰出青年科学基金
2009年度教育部“新世纪优秀人才”入选者
2005年国家自然科学奖二等奖
