【学习和工作经历】

  • 2024/09-                 中山大学    医学统计学系    副教授、博士生导师
  • 2021/05-2024/09    中山大学    医学统计学系   副教授、硕士生导师
  • 2017/07-2021/03    纽约州立大学UAlbany       博士后
  • 2012/09-2017/06    中山大学    医学统计学系   硕博连读
  • 2007/09-2012/06    宁波大学    医学部            本科

【个人概述】

    医学统计学系副教授、博士生导师,主要研究方向为因果推断和因果中介分析方法改进及应用。主持国自然、广东省自然、广州市科技局项目等;以第一或通讯作者在国际高水平期刊发表论文60多篇,被引>2800,H-index为30;研究成果受到路透社(Reuters)、CNN、国会山报(the Hill)等国际知名媒体的报道和国际同行的高度评价。入选中山大学“百人计划”人才引进项目(2021)、广东省“珠江人才计划”青年拔尖人才项目(2022)、中国科协“青年人才托举工程”项目(2023)等。此外担任全国公共卫生与预防医学名词编写委员会秘书、广东省“百千万工程”卫生健康领域专家库成员、中华预防医学会继续教育分会青年委员组组长、广东省预防医学会健康医疗大数据专业委员会委员,此外担任《Research》、《新医学》、《华南预防医学》等期刊青年编委等。

【主要课题方向】

  • 基于观察性数据的因果推断方法改进。
  • 混合暴露健康因果效应评估方法改进。
  • 因果中介分析方法改进。
  • 基于因果推断及因果中介分析方法的环境暴露健康效应研究。

    *博士生课题以统计方法学改进为主,硕士和博士后课题根据前期背景商定。欢迎感兴趣的同学来邮咨询~

【研究项目】

  • 2023/01-2025/12  气象因素和大气污染的心肺健康因果效应评估及时空因果推断模型研究,国家自然科学基金青年项目(82204162),主持 
  • 2023/04-2025/03  环境暴露的社区易感性指数的构建研究,广州市科技局(2023A04J2072),主持
  • 2022/01-2024/12  气象与细颗粒物的交互作用对血脂代谢的影响及其易感因素和机制初探,广东省自然科学基金面上项目(2022A1515010823),主持 
  • 2023/01-2023/12  基于因果中介推断的“绿地暴露-空气污染-心血管疾病”路径探索研究,高校基本科研业务费青年教师培育项目(23qnpy108),主持
  • 2018/02-2022/01  Assess and model the health effects, population, and infrastructural vulnerabilities of power outage, 美国国立卫生研究院(NIH),统计负责人
  • 2019/10-2023/09 Evaluating short-/long-term impacts and exposure sources of ultrafine particles on multiple health outcomes in New York State by using high-resolution pollutant simulations,纽约州能源研究与发展部门(NYSERDA),统计负责人(2019/10-2021/03)
  • 2017/07-2018/12 Impact of environmental policies and changes in air pollution levels, particle composition, and cause-specific hospital admission rates in New York State,纽约州能源研究与发展部门(NYSERDA),统计负责人
  • 2015/01-2017/07 手足口病气象、社会经济和人口学危险因素研究,国家自然科学基金面上项目,参与

【部分论文列表】

  • Wu G., Wang S., Wu W.,  Benmarhnia T., Lin S., Zhang K., Romeiko X., Gu H., Qu Y., Xiao J., Deng X., Lin Z., Du Z.#, Zhang W.#, Hao Y#. Potential causal links of long-term PM2.5 components exposure with diabetes incidence and mortality in the United States. Sustainable Cities and Society (2025), 106071. //doi.org/10.1016/j.scs.2024.106071
  • Li, Z., Wu, W., Huang, Y., Lawrence, W. R., Lin, S., Du, Z., Wang, Y., Hu, S., Hao, Y., & Zhang, W.#. Urban Residential Greenness and Cancer Mortality: Evaluating the Causal Mediation Role of Air Pollution in a Large Cohort. Environmental Pollution (2024), 124704. //doi.org/10.1016/j.envpol.2024.124704
  • Zhang, Y., Chen, S., Wei, J., Jiang, J., Lin, X., Wang, Y., Hao, C., Wu, W., Yuan, Z., Sun, J., Wang, H., Du, Z.#, Zhang, W.#, & Hao, Y.#, Long-term PM1 exposure and hypertension hospitalization: A causal inference study on a large community-based cohort in South China. Science Bulletin (2024). //doi.org/10.1016/j.scib.2024.03.028 
  • Li, Z., Wang, Y., Wu, W., Zhao, Y., Wang, S., Wang, P., Lin, X., Gong, Y., Wu, Z., Li, X., Sun, J., Zhao, N., Huang, Y.#, Hu, S.#, & Zhang, W.#, The relative contribution of PM2.5 components to the obstructive ventilatory dysfunction—insights from a large ventilatory function examination of 305,022 workers in southern China. Environment International (2024), 187, 108721. //doi.org/10.1016/j.envint.2024.108721 
  • Wu, W., Chen, D., Ruan, X., Wu, G., Deng, X., Lawrence, W., Lin, X., Li, Z., Wang, Y., Lin, Z., Zhu, S., Deng, X., Lin, Q., Hao, C., Du, Z., Wei, J.#, Zhang, W.#, Hao, Y.#, Residential greenness and chronic obstructive pulmonary disease in a large cohort in southern China: Potential causal links, risk trajectories, and mediation pathways, Journal of Advanced Research (2024), doi: //doi.org/10.1016/j.jare.2024.05.025
  • Sun X, Lin X, Yao J, Tian T, Li Z, Chen S, Hu W, Jiang J, Tang H, Cai H, Guo T, Chen X, Chen Z, Zhang M, Sun Y, Lin S, Qu Y, Deng X, Lin Z, Xia L#, Jin Y#, Zhang W.#, Potential causal links of long-term exposure to PM2.5 and its chemical components with the risk of nasopharyngeal carcinoma recurrence: A 10-year cohort study in South China. International Journal of Cancer (2024);1‐9. doi: //doi.org/10.1002/ijc.35047 
  • Wang Y, Wang Z, Jiang J, Guo T, Chen S, Li Z, Yuan Z, Lin Q, Du Z, Wei J, Hao Y, Zhang W#. The Effect of Long-Term Particulate Matter Exposure on Respiratory Mortality: Cohort Study in China. JMIR Public Health Surveill (2024);10:e56059. doi: //doi.org/10.2196/56059
  • Wang, X., Zhang, Y., Tarik, B., Zhang, K., Lin, S., Deng, X., Gu, H., Wu, W., Lin, X., Du, Z., Wang, Y., Qu, Y., Lin, Z., Zhang, M., Sun, Y., Dong, G., Wei, Y.#, Zhang, W.#, & Hao, Y#. The effect of residential greenness on cardiovascular mortality from a large cohort in South China: An in-depth analysis of effect modification by multiple demographic and lifestyle characteristics. Environment International (2024), 190, 108894. //doi.org/10.1016/j.envint.2024.108894
  • Wang, S., Ma, Y., Wu, G., Du, Z., Li, J., Zhang, W.#, Hao, Y. Relationships between long-term exposure to major PM2.5 constituents and outpatient visits and hospitalizations in Guangdong, China. Environmental Pollution (2024), 123866. //doi.org/10.1016/j.envpol.2024.123866 
  • Lin X, Jin Y, Yao J, Sun X, Tian T, Li Z, Chen S, Jiang J, Hu W, Hao Y#, Xia L#, Zhang W#. Adverse prognosis of nasopharyngeal carcinoma following long-term exposure to multiple air pollutants. Environmental Chemistry Letters (2023), doi: //doi.org/10.1007/s10311-023-01659-2 
  • Wu, W., Wu, G., Wei, J., Lawrence, W. R., Deng, X., Zhang, Y., Chen, S., Wang, Y., Lin, X., Chen, D., Ruan, X., Lin, Q., Li, Z., Lin, Z., Hao, C., Du, Z., Zhang, W.#, & Hao, Y.#, Potential causal links and mediation pathway between urban greenness and lung cancer mortality: result from a large cohort (2009 to 2020). Sustainable Cities and Society (2023), 105079. //doi.org/10.1016/J.SCS.2023.105079 
  • Guo T, Chen S, Wang Y, Zhang Y, Du Z, Wu W, Chen S, Ju X, Li Z, Jing Q, Hao Y, Zhang W#. Potential causal links of long-term air pollution with lung cancer incidence: From the perspectives of mortality and hospital admission in a large cohort study in southern China. International Journal of Cancer (2023). doi: //doi.org/10.1002/ijc.34699 
  • Wang Y, Wei J, Zhang Y, Guo T, Chen S, Wu W, Chen S, Li Z, Qu Y, Xiao J, Deng X, Liu Y, Du Z#, Zhang W#, Hao Y#. Estimating causal links of long-term exposure to particulate matters with all-cause mortality in South China. Environment International (2023),171:107726. doi: //doi.org/10.1016/j.envint.2022.107726 
  • Lin, X., Tian, T., Shi, C., Wang, P., Chen, S., Guo, T., Li, Z., Liang, B., Zhang, W.#, Qin, P.#,  Hao, Y. What are the individual and joint impacts of key meteorological factors on the risk of unintentional injuries? A case-crossover study of over 147,800 cases from a sentinel-based surveillance system. Sustainable Cities and Society (2023), 91, 104413. //doi.org/10.1016/J.SCS.2023.104413 
  • Cai H, Du Z, Lin X, Lawrence WR, Hopke PK, Rich DQ, Lin S, Xiao J, Deng X, Qu Y, Lin Z, Wang X, Ju X, Chen S, Zhang Y, Wu W, Wang Y, Gu J, Hao Y#, Zhang W#. Interactions between long-term ambient particle exposures and lifestyle on the prevalence of hypertension and diabetes: insight from a large community-based survey. Journal of Epidemiology & Community Health (2023): jech-2023-220480. doi: //doi.org/10.1136/jech-2023-220480 
  • Qu Y*, Zhang W*, Boutelle AM, Ryan I, Deng X, Liu X, Lin S. Associations Between Ambient Extreme Heat Exposure and Emergency Department Visits Related to Kidney Disease. American Journal of Kidney Diseases (2022): S0272-6386(22)00918-0. doi: //doi.org/10.1053/j.ajkd.2022.09.005 
  • Zhang, W.*, Gao, M.*, Xiao, X.*, Xu, S.-L., Lin, S., Wu, Q.-Z., Chen, G.-B., Yang, B.-Y., Hu, L.-W., Zeng, X.-W., Hao, Y., Dong, G.-H., Long-term PM0.1 exposure and human blood lipid metabolism: New insight from the 33-community study in China. Environmental Pollution (2022). 119171.
  • Zhang W, Sheridan S, Birkhead G, Croft D, Brotzge J, Justino J, Stuart N, Du Z, Romeiko X, Ye B, Dong G, Hao Y, Lin S. Power Outage: An Ignored Risk Factor for Chronic Obstructive Pulmonary Disease Exacerbations. CHEST (2020); 158 (6): 2346-2357.
  • Zhang W, Kinney P, Rich DQ, Sheridan SC, Romeiko XX, Dong G, Stern EK, Du Z, Xiao J, Lawrence WR, Lin Z, Hao Y, Lin S. How Community Vulnerability Factors Jointly Affect Multiple Health Outcomes after Catastrophic Storms. Environment International (2020); 134: 105285.
  • Zhang W, Spero TL, Nolte CG, Garcia VC, Lin Z, Romitti PA, Shaw GM, Sheridan SC, Feldkamp ML, Woomert A, Hwang S-A, Fisher SC, Browne ML, Hao Y, Lin S. Projected Changes in Maternal Heat Exposure During Early Pregnancy and the Associated Congenital Heart Defect Burden in the United States. Journal of the American Heart Association (2019); 8 (3): e010995.
  • Zhang W, Lin S, Hopke PK, Thurston SW, van Wijngaarden E, Croft D, Squizzato S, Masiol M, Rich DQ. Triggering of cardiovascular hospital admissions by fine particle concentrations in New York state: Before, during, and after implementation of multiple environmental policies and a recession. Environmental Pollution  (2018); 242: 1404-1416.

【会议报告】

  • 张王剑、张昱勤、郝元涛等,考虑暴露溢出效应的时空因果推断模型构建及应用,2024中国生物统计学术会议,广东广州,2024/7
  • 张王剑、吴文静、郝元涛等,绿地暴露与肺癌死亡风险间的因果效应及其中介机制研究,2023中国生物统计学术会议,山西太原,2023/7
  • Zhang W, Lin S. The association between power outage and the exacerbation of Chronic Obstructive Pulmonary Disease (COPD). The 31st Annual Scientific Conference of the International Society of Environmental Epidemiology (ISEE), Utrecht, Netherlands; 2019.
  • Zhang W. How Community Vulnerability Factors Jointly Affect Multiple Health Outcomes after Catastrophic Storms. Panelist at the Resilience In Sustainable rEconstruction (RISE) National Conference: Transforming University Engagement In Pre- and Post-Disaster Environments: Lessons from Puerto Rico, 11/18/2019.
  • Zhang W, Lin S, Hopke P, Thurston S, Wijngaarden E van, Croft D, Squizzato S, Masiol M, Rich D. Does the Association between Cardiovascular Hospital Admissions and Fine Particle Concentrations Change Before, During, and After Implementation of Multiple Environmental Policies? The New York State Accountability Study. The 30th Annual Scientific Conference of the International Society of Environmental Epidemiology (ISEE), Ottawa, Canada; 2018.

【R软件程序包】

  • Zhang W, Du Z, Deng X, Ye Bo, Lin Z, Yao J, Jin Y, Lawrence WR, Hao Y. rSPARCS: Sites, Population, and Records Cleaning Skills. 2018. Available at //cran.r-project.org/package=rSPARCS.
  • Du Z, Zhang W, Hao Y. gamRR: Calculate the RR for the GAM. 2018. Available at //cran.r-project.org/package=gamRR .
  • Lin Z, Laska E, Siegel C, Zhang W, Lin Q, Ye B. CRWRM: Changing the Reference Group without Re-Running the Model. 2019. Available at //CRAN.R-project.org/package=CRWRM. 
  • Deng X, Zhang W, Lin S. APML: An Approach for Machine-Learning Modelling. 2020. Available at //CRAN.R-project.org/package= APML. 

【媒体采访及报道】

  • 接受STAT news科学记者采访,针对一篇发表在Science Advances上的文章进行评论。//www.statnews.com/2020/11/04/covid19-coronavirus-air-pollution/
  • Climate change could raise risk of congenital heart defects. Reuters. 02/19/2019. //in.reuters.com/article/us-health-heart-defects/climate-change-could-raise-risk-of-congenital-heart-defects-idINKCN1Q82NE
  •  Climate change could hurt babies' hearts, study says. CNN. 01/30/2019. //www.cnn.com/2019/01/30/health/climate-change-congenital-heart-defects-study/index.html
  • Climate change may increase congenital heart defects. American Heart Association & Science Daily. 01/30/2019. //newsroom.heart.org/news/climate-change-may-increase-congenital-heart-defects & www.sciencedaily.com/releases/2019/01/190130075748.htm.
  • Study: Climate change could lead to worse heart defects in babies. The Hill. 01/30/2019. //thehill.com/policy/healthcare/427647-study-climate-change-could-cause-heart-defects-in-babies

【参编教材与论著】

  • 《卫生信息资源规划与管理》第1版,人民卫生出版社,2023年,编委
  • 《医学统计学实习指导及习题集》第1版,人民卫生出版社,2016年,参编人员
  • 《医学统计学》第1版,北京大学医学出版社,2013年,参编人员

【指导学生参加大创项目情况】

  • 2023年,基于因果中介推断的大气污染物在绿地暴露和心血管疾病死亡风险之间的复杂作用分析(马玉洁、王爽、王卓浩),国家级,入选第17届全国大学生创新年会(2024,成都)
  • 2023年,基于因果推断和混合暴露评估方法研究长期空气污染暴露的人群健康效应(赵丹桂、廖思萍、叶佩雯),校级
  • 2022年,基于空间因果推断的大气污染-心血管疾病死亡风险研究(林钰纯、赵延婕、陈柳府),国家级

【指导学生获奖情况】

  • 2024年,考虑暴露溢出的时空因果推断模型构建及其在大气颗粒物心血管健康效应评估中的应用(张昱勤),中山大学优秀博士毕业论文
  • 2024年,基于因果中介分析的邻苯二甲酸酯—血脂—心血管疾病死亡中介路径研究(马玉洁),中山大学优秀本科毕业论文
  • 2024年,贝叶斯核机器回归模型在大数据时代的算法优化与验证研究(蔡欢乐、唐慧、陈丹),第十届全国大学生统计建模大赛广东赛区研究生组三等奖
  • 2024年,基于机器学习算法的高度近视白内障手术屈光预后的预测模型构建(杨艺轩、刘丽敏、王子琳),第十届全国大学生统计建模大赛广东赛区本科生组三等奖
  • 2023年,基于因果中介推断的大气污染物在绿地暴露和全因死亡风险之间的复杂作用分析(王爽、马玉洁、王卓浩),第九届全国大学生统计建模大赛广东赛区本科生组一等奖、国赛三等奖
  • 2023年,多环芳烃组分混合暴露对全死因死亡的因果推断(蔡欢乐、唐慧、陈丹),第九届全国大学生统计建模大赛广东赛区研究生组二等奖
  • 2023年,基于双重差分法探索PM2.5及其组分对医院门诊就诊量的影响研究(张率骐、郑子涵、李坤英),第九届全国大学生统计建模大赛广东赛区本科生组一等奖
  • 2023年,中国中老年人共病对家庭卫生经济负担的影响——基于因果推断研究(陈诗敏、李知强、王旭),第九届全国大学生统计建模大赛广东赛区研究生组三等奖
  • 2022年,基于cox边际结构模型的时依暴露因素的因果效应估计(张昱勤、陈世瑞、郭童),第八届全国大学生统计建模大赛广东赛区研究生组三等奖
  • 2022年,贝叶斯空间模型在中国肺结核数据分析中的应用(林钰纯、陈柳府、赵延婕),第八届全国大学生统计建模大赛广东赛区本科生组一等奖

【社会兼职】

  • 全国公共卫生与预防医学名词编写委员会秘书
  • 中华预防医学会继续教育分会青年委员组组长
  • 广东省预防医学会健康医疗大数据专业委员会委员
  • Research杂志青年编委
  • 《新医学》杂志青年编委
  • 《华南预防医学》杂志青年编委

【招生方向】

  • 专业背景:数学、统计学相关专业、预防医学等。
  • 重点考察:自学和独立解决问题的能力、数理统计知识、编程能力、沟通和协作能力、英文写作能力。
  • 欢迎专注学术的本科生、硕士、博士、博士后加入我们团队!